This is how I do it. YMMV. I’ve used DEVONthink since its early days. If you’re unfamiliar with DEVONthink, it’s a knowledge management tool that allows you to save information, tag it, cross-reference it and classify it. Since I use both a laptop and a desktop Mac Pro, I need to synchronize databases across machines. There are several ways to go about synchronization: Direct connection This is not a bad option when both machines are turned on simultaneously and are connected to the same network.